467: Neurosurgeon Discovers Key To Mitochondrial Health

Ashley James And Dr. Jack Kruse


  • What are mitochondria
  • Mitochondrial DNA vs. RNA and DNA
  • Mitochondria are only inherited from mothers
  • What is leptin
  • Three pillars of supreme mitochondrial biology

In this episode, neurosurgeon Dr. Jack Kruse talks about a different perspective on achieving optimal health. He also shares the importance of mitochondria, the three pillars of supreme mitochondrial biology, and the things we can do to live a longer life.


Hello, true health seeker and welcome to another exciting episode of the Learn True Health podcast. Today is a doozy and I'm so excited that you are here to learn from Dr. Jack Kruse, really interesting information he has to share with us today. I ask you to keep an open mind, and I just think the best interviews are the kind that challenges our belief systems and allows us to learn something totally new that's outside of our reality. Remember the movie The Matrix so many years ago, like 20 years ago when Neo takes the pill and all of a sudden wakes up in The Matrix and you're like, whoa, I did not know that that is where that movie was going? It's kind of like that. It's the what you don't know you don't know.

That's wherein lies the biggest help for you because you know you should go to bed on time, drink water, move your body like exercise, and you know you should eat healthy. Those are all good things right, but if you're here to learn true health, then you're really here to learn things you don't know you don't know. And I just love Dr. Jack Kruse for that. He is here to teach a lot of what we don't know we don't know. And in fact, I'm sure that after this interview, you'll want to follow him and continue to learn from him.

Now I don't believe in any one diet dogma because I believe that healing is a journey and that we should learn from all the people and all the experts, and then figure out how to apply what works for us to us. So just listen with a really open mind. Today he shares some great information about how we can improve significantly the health and function of our cells. Specifically, a part of our cells is called the mitochondria, which is the powerhouse of the cell. 

The difference between you and a cadaver is a cadaver’s mitochondria has stopped, right? There's no more energy production, the cells aren't producing any more cellular fuel, right? You are alive, your mitochondria is alive, and there's a lot going on in the world that is dampening, that is hampering, that is harming your mitochondria.

So he is here to teach us things that we can do really easy as in very accessible things that we can do to immediately and drastically improve our mitochondrial health and thus improving all hormones in the body and bringing into balance blood sugar, leptin, and also strengthening the innate arm of the immune system. So, great information. Just strap on and just remember, he's going to challenge your belief systems and I think that's a good thing. Please share this podcast with those you care about who also would appreciate a wonderful challenge to their belief systems, and give them great information to improve their mitochondrial health as well. 

I'd love for you to join the Learn True Health Facebook group if you are like me and you're interested in joining a community of like-minded true health seekers that are looking to support each other along their health journey. So just search Facebook for Learn True Health, or you can go to learntruehealth.com/group to join. You can also go to learntruehealth.com to search for all the other podcasts we have. There are lots of show notes and you can use the search function to find those episodes. I'd love to have you join the email list if you ever want to just stay updated as things progress. Just keep sharing, keep listening, and please join the podcast Facebook group, love to see you there as well.

And also, we are on LBRY, so if you are a listener or a new listener and you want to know where to find us, you can find us at any podcast directory including LBRY. Awesome. Have yourself a fantastic rest of your day and enjoy today's interview.

[00:04:23] Ashley James: Welcome to the Learn True Health podcast. I’m your host, Ashley James. This is episode 467. I'm really excited for today's guest. We have with us Dr. Jack Kruse. Dr. Kruse, I've had several of my past guests reference your work, and I've actually had several listeners request to interview you, and I just keep hearing your name over and over. So I'm so glad to finally have you on the show. Welcome.

[00:04:55] Dr. Jack Kruse: No problem. Appreciate it.

[00:04:57] Ashley James: Yeah, absolutely. I'm really intrigued by your work. Now listeners can go to jackkruse.com, and of course, the links to everything that Dr. Kruse does are going to be in the show notes of today's podcast at learntruehealth.com. Before we dive into you teaching us and sharing with us exactly what you do, can you tell us the story of what happened that led you to the work that you do now?

[00:05:24] Dr. Jack Kruse: Well, I mean, life happened to me, to be quite frank with you. It's a story where being an allopathic neurosurgeon, I was doing things that I was taught to do both in residency and medical school, and I began to find that some of the things that I was doing really weren’t benefiting patients long term. I began to question, was I doing the right things for my patients? And then ultimately, it then happened to me. I wound up gaining quite a bit of weight after residency and I tore a knee meniscus at a spine meeting that I was giving a talk at.

And one of the orthopedic surgeon’s wives who happened to work for a biotechnology company that actually knew the reason why this happened to me, and she said, look, I want you to read these six papers. I'm going to give you a book to read. Long story short, what she was trying to tell me was the company she was working for was cooking the books on a hormone called leptin. They had synthetic leptin and they began to realize certain things about leptin, and all these papers that she sent me, she was actually trying to out her company but I actually went a different way.

I actually realized that what fundamentally she had done for me was answer the key question that my medical training was basically given to me by a centralized controller, specifically big pharma, which came from a lot of the political history of the United States in terms of medicine. What I realized is that leptin fundamentally works within a decentralized network, which is what nature and decentralized networks, one of the fundamental tenets of them is they don't have any central controller, meaning there's no CEO, there's no boss, but they work on something called negative or positive feedback loops. It turns out the negative and positive feedback loop that leptin works on is actually the light and dark cycle. That hormone controls all energy balance in your body.

So after about 18 months of doing all my homework on this when I realized most of the things that I learned in medical school were wrong because they came from the centralized controller, which was big pharma, I began to ask better questions. And when I asked better questions, I started to realize that the focus that medicine is on right now is RNA and DNA, and the real focus that we need to be on is actually mitochondrial DNA because that's where energy is transformed from the environment in. And when you begin to focus on that, people magically do better. That's kind of how it started almost 16, 17 years ago now.

[00:08:10] Ashley James: It's very apropos what you said about how your realization that your medical training was largely influenced by politics and the pharmaceutical industry, and that's what we see when we look at the creation of allopathic medicine over the last 115 years. That the pharmaceutical companies were investing in the universities that would teach drug-based medicine only and guide them.

[00:08:43] Dr. Jack Kruse: You need to understand the reason why that happened. It's actually not a medical reason, it's actually an economic reason, and it goes back to the breakup of Standard Oil. When Teddy Roosevelt came in after McKinley was assassinated and he took apart Standard Oil, if you ever go back and read what Rockefeller said in his testimony in front of Congress and Teddy Roosevelt said, come hell or high water, I will make sure that you pay for this. 

And to this very day, I always point this out to people that all the components that were Standard Oil eventually became big pharma, why? Because now all the chemicals that they created in their petroleum products were reconstituted and then what Rockefeller decided to do by hiring Abraham Flexner, this went on to the Flexner Report. Everybody loves to think that this was an entirely new industry, no it wasn't a new industry. What it was was repurposing waste chemicals in a new way, and Rockefeller had gotten these ideas over the last 30, 40 years of his life that he actually could do that.

To this very day, if you look at where big pharma is incorporated, they're all incorporated in New Jersey, and that's exactly where Standard Oil was incorporated. That fact has not changed today. The problem is most modern humans don't understand truly how this happened. They believe that it's a biologic story and it's not. It was an economic story, and it was a robber baron seeking to bankrupt the US Federal government. And I have to tell you that I think Rockefeller has done a pretty masterful job over the last 115 years on this planet.

[00:10:25] Ashley James: Not only do they put the byproducts in the medicine, but they've also put it in our cosmetics. It is in our detergents and the cosmetics that then get on our skin and get absorbed that way as well. It's pretty ridiculous when we look to see the byproducts of these different industries and how they end up in our body when they clearly shouldn't be. How does that affect the mitochondria? So you're saying the key to health is making sure the mitochondria is functioning, the DNA of the mitochondria is functioning. How do these man-made chemicals affect the mitochondria?

[00:11:14] Dr. Jack Kruse: Well, the effect varies depending on the class of drugs you're talking about, but here's the general gist that people need to know. Allopathic medicine has kept the focus on RNA and DNA. We learned about RNA and DNA in ‘53 from Watson and Crick. Big pharma has always kept the gun barrels for drug development there, why? Because they knew if we could never get an answer, you're just going to be able to create products for customers that they need constantly and it's a good business model. They've been very successful with it.

For those in your audience that really don't understand cell biology well, you just need to know that mitochondria is an organelle within a cell that provides all the energy that life creates from the environment around it in terms of making things work. So when I make the comment to people that not all the atoms in the cell are nonliving, taken apart, the organization, however, are those atoms with the energy that's contained in the cell is what takes them abiotic atom and actually allows it to act in the orchestra so that it appears to be alive. And really, what the life force is all about is about the organization of energy so that it can transform both information and energy into useful physiologic work.

So when you understand that, basically mitochondria transforms energy from the sun and turns it into something useful that we can use to do physiologic work at some level. So, when a person is dead, we have a name for it. It’s called a cadaver. What is a cadaver? A cadaver is a person that is a bunch of atoms that have no energy that's organizing their physiologic action. People who are alive actually do have the ability to use their mitochondria to transform the things that can absorb, reconstitute, and transform energy into something useful, that cell is me. And it turns out that mitochondrial efficiency determines your health span and it determines your longevity.

It turns out as energy transformation is reduced, that's where illness comes, and when it gets to a critical mass that's when you die. So in this paradigm, that was really laid out probably close to 50 years ago by a guy named Doug Wallace who's now at the Children's Hospital Philadelphia, he's the Ph.D. that found out that all mitochondria only inherited from our mom, it's not inherited from our dad. So it turns out that our mom gives us the power plant that allows us to live. 

So that means that mom or the maternal side is far more important in understanding the trajectory of patients’ lives especially early on, and then how to maximize mitochondrial function going forward. It turns out, many of the things that are operational for mitochondrial DNA are not operational and incongruent with the things that we know about regular RNA or DNA that's found in the nucleus. It turns out that energy production from mitochondria is actually what turns on RNA and DNA inside the nucleus, and why is that important? Because it basically means that the way life manifests—meaning the phenotype of different diseases or different healthy states—is totally reliant on how well or poorly you transform energy into mitochondria.

[00:14:50] Ashley James: Now you had mentioned earlier that you began this diving into leptin. Can you explain what leptin is?

[00:14:59] Dr. Jack Kruse: Leptin is a hormone that's found in humans in their subcutaneous fat that actually goes to tell the brain at the hypothalamic level—that's in a part of your brain that's right behind your pituitary gland—what the energy balances of the body. Since you've heard me talk about mitochondria earlier, you begin to realize that medicine really is a thermodynamic gain and not the gain that everybody else talks about. It's about thinking like an engineer, and leptin happens to be information from the distal part of the body, meaning the subcu fat, to the brain what energy status is in different parts of the body. 

The way leptin works in humans, it only enters the hypothalamus when it's dark, usually right around midnight to about 3:00 AM. And that's where the information transfer occurs between leptin and the hypothalamus. If that information transfer is not uploaded properly, similar to how you would think about the USB drive through your computer, the brain never gets that information, you become leptin resistant, then you're subject to many different diseases—obesity being one, but many other diseases are also on there as Doug Wallace has laid out in his 50 years of research. That's basically how it works.

[00:16:20] Ashley James: So if someone is a night owl and doesn't go to bed till 1:00 in the morning, or if someone has poor sleep and basically…

[00:16:28] Dr. Jack Kruse: They should buy term life insurance.

[00:16:33] Ashley James: Oh geez.

[00:16:35] Dr. Jack Kruse: That’s the truth.

[00:16:36] Ashley James: So you said that this is all about the light-dark cycle, I'm just thinking about those for people that live near the North Pole where they get months and months of only summer or months and months of only dark. Are you saying we really should be very careful about balancing the circadian rhythm and avoiding blue light?

[00:16:57] Dr. Jack Kruse: If you don't do that, you're guaranteeing that you're going to be a customer of big pharma, that's really the key. And the key is, once you begin to realize that nature is the only decentralized network that's natural on earth, you need to understand how it works. This is the reason why, if you look at planet Earth—just to make this very clear to you—we have boreal forests, which are the last living structure in the Northern Hemisphere. We don't have that in the southern hemisphere because we only have Antarctica. 

But above the boreal forest, which is right around the 59th latitude, Earth is not hospitable to life. That should actually clue you in to, hey, maybe strong magnetic fluxes from the Aurora Borealis and maybe the really poor light and dark cycle that you have with the seasons up there is somehow not optimized to mitochondrial biology. That's the reason why evolution or God—whoever you believe in most—has not put living things above the boreal forest. And the reason why this should make sense to you is remember what the boreal forest does, it's the largest secretor of oxygen on planet Earth. And remember, oxygen is the terminal electron acceptor for mitochondria. So for those of you who think this is hyperbole, you need to know how all the pieces fit to really understand disease and wellness. It turns out that oxygen is extremely important in the dance that life does, and it turns out the amount of oxygen we really need is completely linked to the amount of light that the system gets both through the skin and through the eyes. That's actually how leptin works.

And when you begin to see these pieces fit, then you begin to understand why it is when a young kid looks at their cell phone 150 times a day and the blue light screen is 5750 Kelvin light, which mimics mean when you're telling the brain 150 times a day even when it's dark out that it's solar noon, you can see how that creates a problem with chaos in the hypothalamus that leptin can't work. You have nasal chaos in medicine that's called inflammation and inflammation leads to leptin resistance and leptin resistance leads to the diseases that are associated with poor leptin biology for energy and information transfer and things like obesity.

[00:19:15] Ashley James: So I know you've been touching on this, but could you lay it out for us to understand what is the connection between having healthy levels of leptin and having healthy mitochondria?

[00:19:29] Dr. Jack Kruse: Actually, I don't think you should think about healthy leptin levels and I think that's one of the fallacies of functional medicine. They want you in the paradigm where you start to think about healthy levels of everything. It doesn't matter what lab you're talking about, why? Because they functionally make the same mistake that allopathic doctors do. They think somehow that looking at your cholesterol level somehow has any thermodynamic relevancy or face validity to understanding truly what's going on at the cellular level and they don't.

And the reason why they're the same is because the allopathic doctors who they love on social media give you prescriptions for statins, vaccines, and all kinds of things like that. What do they do? They turn around and sell you supplements. They're basically doing the same thing. It just has a different idea. It's basically propaganda, and with propaganda, I will tell you marketing is legalized lying. They get away with it, and the reason they get away with it is because allopathic doctors are functionally taught to look at RNA and DNA and not think thermodynamically about people.

When you begin to think about the thermodynamics that people through mitochondrial biology and leptin biology, you begin to realize that everything is about information and energy. And it turns out that leptin biology optimizes that. If you learn how to use the light and dark cycle, how to use water, and how to use magnetic effects because those are the three pillars that form supreme mitochondrial biology. Once you optimize those, magically the diseases that have afflicted you over a period of time start to go away without you needing some supplements or a prescription for a statin.

[00:21:10] Ashley James: So you said water, light, and magnetic effects are the three keys to having a mitochondrial function.

[00:21:18] Dr. Jack Kruse: Correct. We call it light, water, and magnetism. It’s the three-legged stool of life. Where did that start? It started with NASA. NASA and SETI look for life on other planets by utilizing those three things. 

To give you a good frame of reference, let's take the next planet. The next planet is Mars. It's dead and it's red. It's a giant desert. It has the sun driving most of its processes. As a planet, the spectrum, however, is different because it has no atmosphere. The reason it has no atmosphere is because it has no magnetic field. And it turns out there is water on Mars, but it's frozen at the polar ice caps. So just the presence of light, water, and magnetism doesn't mean that you can be optimized, which is part of the reason why it's a joke that our friend Elon Musk wants to go to a dead red desert in the sky. It absolutely makes no sense, but it only makes sense if you think about it probably from a different viewpoint.

My viewpoint is that life on Earth is optimized because light, water, and magnetism operate in a certain way. Light is important for leptin, and it turns out, mitochondria—if you know anything about mitochondria, most people who are not science bases, I know that you've all heard about photosynthesis. Photosynthesis forms the entire food web on planet Earth. There's not a food that you can think of in your mind right now that's not directly linked to photosynthesis. The only foods that don't fit there are processed foods that are made in the lab, why? Because they’re not made in sunlight. That's the reason you shouldn't eat them. It's not for any other reason.

The key is when you understand that photosynthesis basically takes CO2 from plants, takes water from the hydrologic cycle on Earth, and uses sunlight to create glucose [inaudible 00:23:17]. What does mitochondria do? It fundamentally reverses the process of photosynthesis. So what do we do? We take sugar and we break it back down to CO2, which we expel or exhale, and we make water. We make water at a very specific place in our body. The water we make is made at cytochrome c oxidase, which is a cytokine four in the mitochondria. Most allopathic doctors, most functional medicine doctors don't even know that basic. They don't even know that mitochondrial respiration reverses the photosynthetic product.

Most people in allopathic medicine and functional medicine look at food from the viewpoint of carbohydrates, proteins, and lipids, Jack Kruse does not. Jack Kruse knows that all foods are an electromagnetic barcode of electrons and protons tied to the photosynthetic qualitative programs that are found in nature. You need to think about food that way. And what do mitochondria do, or anybody who's ever studied mitochondria knows that the input to mitochondria is called electron chain transport. It's not called protein, lipid, or carbohydrate transport. It's called electron chain transport.

Then there's this fifth cytochrome that everybody in allopathic medicine and functional medicine seems to know about but has no earthly idea how it fits into the fabric of nature. It's called the ATPase. The ATPase is what makes some of the energy. A better way to think about it is it transforms the energy that's present in food to something we can use electromechanically in cells to derive life and life principles in terms of physiology. It turns out, the ATPase functionally works both with electrons and protons. In fact, it needs 3.4 protons from inside the mitochondrial matrix to spin it one time in its [inaudible 00:25:15] head to make one ATP.

When you begin to see the processes inside mitochondria and how they transform energy from the sun into energy that we can use for physiologic work, then and only then do you have a concept of truly how we build health and how we build illness.

[00:25:37] Ashley James: So, besides eating foods that require photosynthesis, like you said, does our body—and I've heard this, a past guest mentioned this…

[00:25:47] Dr. Jack Kruse: Let me stop you for a moment because you just skipped over a really big problem.

[00:25:51] Ashley James: What's that?

[00:25:52] Dr. Jack Kruse: Where do you live?

[00:25:54] Ashley James: Washington state.

[00:25:56] Dr. Jack Kruse: Perfect. So, let me ask you a question based on what I just told you because if you skip over this part you're bound to make this mistake. If you're in Washington State on December 31 and you go to Whole Foods and eat a pineapple, do you think that nature has a problem with that?

[00:26:12] Ashley James: Actually I do.

[00:26:15] Dr. Jack Kruse: Good, because then you understood what I just said. Because see, photosynthesis doesn't provide pineapples to grow at your latitude. You know what that means? That means you're creating molecular chaos on your cell if you do that. So here's the key point. You're designed to eat a diet that your eyes and skin see every single day. 

So guess what, it has to be congruent, otherwise you create that chaos signal which is inflammation. That means that leptin can't get into the hypothalamus to optimize the mitochondrial engines that are present in every part of your body. And it does that by two program changes that you probably have heard of, some of your listeners may have heard of them as well. It's autophagy and apoptosis. That's fundamentally how we optimize or change energy flux to a cell. If those processes are broken, then you cannot transform energy properly.

[00:27:15] Ashley James: Do you believe in fasting to stimulate autophagy and apoptosis?

[00:27:21] Dr. Jack Kruse: Yeah, not apoptosis but autophagy is definitely stimulated by it. And the key with that is, that's why we have the main breakfast. We're designed to eat while it's still light out. You should never eat late at night because it ruins the leptin melatonin growth hormone pathway that I mentioned early in the hypothalamus. Once that's optimized, then what happens next is you go all the way usually for about 12, 13, 14 hours until you eat your breakfast, and you’re designed to eat breakfast. Within the first 30 minutes to an hour of AM light. That's the way you're designed to work in nature. Unfortunately, that's not the way most modern humans live their life.

[00:28:06] Ashley James: Definitely not. So for those who can't go to bed with the sun and wake up with the sun because of their family schedule or their work schedule.

[00:28:18] Dr. Jack Kruse: Term life insurance.

[00:28:19] Ashley James: Oh my gosh.

[00:28:21] Dr. Jack Kruse: This is the message that you need to get to your viewers, Ashley, and it may be the inconvenient truth in them. You don't get a free pass from nature. You need to realize that you're tied to her quilt, and if the circumstances that you find yourself in are not optimized for the way the game is played, you will wind up with a disease at some level. That's what evolution is telling you, and this is the reason why you get the ideas about survival of the fittest and survival of the wisest because those that are necessarily fit doesn't mean they're wise. You can be fit, live in a blue light world, eating pineapples at the 44th latitude in Washington like some of your listeners probably do, but you will not live long. That's why there's a lot of really good-looking cadavers in cemeteries.

[00:29:15] Ashley James: You mentioned that program cell death, which is the apoptosis, you don't recommend fasting for that. What do you recommend doing to help stimulate that?

[00:29:31] Dr. Jack Kruse: Apoptosis is stimulated by appropriate solar exposure on your skin and your eyes. It's specifically controlled mostly by UV light exposure. That's specifically UVA and UVB. So one of the things that we can tell when someone has good apoptosis present is we can use the vitamin D levels as a proxy. And most people in North America right now have vitamin D's that are horrible, why? Because they don't spend a lot of time outside in the sun.

So for example, I don't know where you are now because we're not doing a video on this. You remember when we started the podcast, you asked me, hey, this background is bad, you know why? Jack doesn't use headphones. Jack does all his podcasts sitting out in the sun. I’m in Destin, Florida right now outside in the sun doing this podcast. I bet you that you're in Washington inside with headphones on.

[00:30:23] Ashley James: In a very dark room.

[00:30:25] Dr. Jack Kruse: There you go. Not only that, I know that you're an hour behind me, so it's 12:25 PM where you are. It’s 1:25 PM where I am. So guess what, this is the time of the day where Jack gets to make vitamin D through his skin and his eyes. So Jack is not going to miss this even though he's excited to talk to Ashley James, why? Because the benefit of technology, doing this so that I can share these ideas with your audience, that's the amazing part of technology. But if I continue to do this inside over and over because I've done 1000 podcasts, that would have a significant problem for my biology. In other words, I become thermally inefficient and I would wind up having to go see my profession or some of these functional doctors who would sell me the marketing tab line, buy my shit so you can get healthy. Unfortunately, that's not how it works.

I always tell people, it's amazing to me that wild animals know how to do this. They don't have any doctors out there and they seem to do just fine in nature. Believe it or not, we're proof, meaning humans are proof that what happened from an evolutionary standpoint, our last few million years, must have been pretty good because we're here today talking about this as proof because back then, there were no fancy foods. There were no restaurants. There were no supermarkets. There was no Gold's Gym. There were no trainers. There were no diet books. But guess what, we're here to show you that nature actually works if you get out of your way. 

The reason I don't have to teach lions and hippos quantum mechanics and mitochondrial biology is because they don't have this quantum computer in their head called the human brain that allows them to break nature's laws, kind of like the laws that we just talked about a little while ago about how you and I are doing this podcast. We can see choices are the hinges of destiny. And the thing is the more choices that you make that follow nature's fundamental laws, the more you can avoid guys like me or the functional medicine doctors.

[00:32:37] Ashley James: I love what you just said, and I'm going to go back and write that down because I absolutely love it and use it as a quote in this interview. Your choices being the hinge to basically every little day, like you said, 1000 podcasts is 1000 opportunities lost to produce vitamin D. So we have light receptors, our cells have light receptors and basically, sunlight is nutrients and everyone is deficient in it. We need to get out in the sun.

[00:33:10] Dr. Jack Kruse: I would tell you that sunlight is not only energy but it's information and we know that, not that I want to take you down this rabbit hole.

[00:33:19] Ashley James: Oh, take me.

[00:33:21] Dr. Jack Kruse: I can tell you that the guy that determines the energy side of the equation, you've probably heard of this, Ludwig Boltzmann, came up with the mathematical proof behind the second law of thermodynamics. And in it, basically the equation, when you look it up on Google or in a book, you'll see that that is an equation that defines entropy.

Here's the interesting part of the story. In 1948, a guy named Claude Shannon who worked for Bell Labs. He was trying to fix information and energy. He's trying to explain it. He’s trying to explain how you can figure out the minimum amount of information in a message, and he used mathematics to figure it out. Ironically, the last thing that he came up with the last equation is an equation that looks exactly like the one that Boltzmann came up for entropy.

So now we know from physics that has been developed over the 20th century from a guy named John Wheeler and another guy named Vopson that actually energy and information are one and the same thing. This is a huge development for people like me who teach about mitochondrial energy production because that means that sunlight is actually not just energy, it's also information. It turns out the chromophores that are in your body that are what you call the light sensors have different physiologic tasks because they provide different physiological information.

So for example, I'm going to teach you something right here about mitochondrial biology because we talked about autophagy and apoptosis. Autophagy is predominantly controlled by light in the 600 to 1000 nanometre range. It turns out that apoptosis is controlled by the light that goes anywhere from about 250 to 400 nanometers, and we have chromophore proteins throughout our body that react to it. 

For example, the number one red light chromophore in the body happens to be water, but the number one red light chromophore in mitochondria is cytochrome c oxidase. It has four different chromophore proteins in the cytochrome c oxidase at 620, 680, 760, and 860. So basically, nature's telling us that she takes four bites of the apple to get her information and this fits because our sun is a G class star and it turns out 43% of sunlight happens to be infrared, a light, which carries 600 to 1000 nanometer light.

So this gets back to the whole story about how leptin biology ties to solar cycles because it turns out the type of light that our star makes optimizes our health. On the apoptosis side, it turns out that the chemical receptors that are important for UV light are something called leptin, which we talked about already, and the other part of it is another chemical called melanopsin and neurons. We have these opsins on our skin and our eye that actually absorb UV light, and neuropsin is present on our cornea and our skin, and it's basically a UVA light detector. It tells us about the intensity. 

Melanopsin is a blue light detector. It tells us about the amount of blue light that's present in our body. And if you understand the physics of organisms, meaning how all cells are optimized, it turns out that there has to be a perfect balance between blue and red light, and red light is almost always the same from the time the sun rises to the sunsets, but blue light is not. It actually increases from sunrise to sunset, and it crescendos right at sunset. In other words, the color temperature of light is greatest about the hour before sunset happens and melanopsin is looking for that signal as the sun falls and drops. As soon as that happens, that's the signal that leptin and melatonin cycles and cortisol cycles pay attention to you in your body. And if those cycles are off because you happen to look at your iPhone 150 times a day after the sun sets, well guess what, you just ruined the way you're designed to work in nature.

[00:38:06] Ashley James: Oh my gosh. And for those that don't know, autophagy is so important because it's cleaning up the dead, damaged tissue. Could you explain a little bit about why autophagy is so important that we make sure that we're stimulating it correctly?

[00:38:23] Dr. Jack Kruse: Yeah. Well, I mean, this one is pretty simple because I like to take this analogy like a Ferrari engine on a Ferrari car. If you buy a Ferrari right off the line in Italy, the car goes 230 miles an hour. The engine is primed and does well. A Ferrari that's four or five years old will only go 230 miles an hour if you have a mechanic that keeps it running in tip-top shape like it was when it came out of the line in Italy. 

It turns out, autophagy is the mechanic in a cell that actually makes sure that everything is optimized. In other words, when the engine in the body somehow has damage in it, autophagy is designed to either recycle the engine to make it better, or if it's really bad, there is signaling in mitochondrial biology that marks the mitochondria for replacement. That's what apoptosis is and it gets rid of the engine completely, and then you are able to use some mitochondrial processes to amplify some of the other mitochondria in the cells so that energy transformation is not hindered long term.

Obviously, the more mistakes you make, the more you affect energy over time, and that's where disease manifests. If you really understand mitochondrial biology as Doug Wallace has laid it out, if you want to understand what aging is it's very simple, it's the loss of energy efficiency in mitochondria that happens each decade, we lose—and this is an average answer—on average, as humans, about 10% of our efficiency every decade we're alive. 

So if you're 60 years old, technically in your seventh decade, that means you have 70% energy loss from what you did as a baby. That means that you have to optimize autophagy in that 30% and apoptosis in that 30% in order to maintain wellness going forward. So it means that as you get older. This information I'm sharing with you is more important, and if you want to hear that directly, does it mean, when you're an old guy like I am, that that's the reason Jack is sitting out in the hot Florida sun on the autumnal equinox talking to Ashley James? You got it.

[00:40:45] Ashley James: And apoptosis is so important because it's programmed cell death. Cancer cells don't do it, and that's why they grow out of control.

[00:40:54] Dr. Jack Kruse: Just think about what you just said there, you're right, cancer cells do not perform apoptosis, but what's the key? I told you that UV light controls that.

[00:41:03] Ashley James: We’re told not to go into UV light. We're told, don't go out, cover yourselves up. You're going to get cancer if you go out in the sun. What you're saying is we have to go out in the sun to prevent cancer to support the body's ability to get rid of it.

[00:41:15] Dr. Jack Kruse: Let's go back to the beginning of the podcast. What did I say Rockefeller told Teddy Roosevelt? Guess what, if you create the narrative that people buy, which is propaganda, don't you think that that made good business sense for the people? And when you consider that the medical school curriculum was the algorithm that Rockefeller used to create a new industry to get it back, and then think about it, his grandsons who are both in the Senate and the House of Representatives. They saw it fit that Medicare bills were passed. Why did they do that? They were trying to bankrupt the American government to pay them back to what Teddy Roosevelt did to their family. 

See when you see how all the pieces fit, then you begin to understand truly why big pharma corrupts medicine, and the problem is, it's not medicine doctors are bad, the problem is most medical doctors are ignorant of the history behind their own profession, and they're completely ignorant of the fact that the medical school curriculum is really the first algorithm that has been built to really suit the profiteers and not patients. Until you find a doctor who understands decentralized medicine, which is what mitochondrial medicine functionally is, you the patient have a target on your back, and that target is from big pharma. If you don't think that that's not ongoing right now in this COVID debate with vaccinations, you're sadly mistaken.

[00:42:50] Ashley James: You know, a lot of my listeners lately have been asking what they can do to prevent, to treat, and also after they've had COVID, how can they recover for some who are still experiencing it?

[00:43:08] Dr. Jack Kruse: So let's talk about that. Does anybody out there know anything about coronaviruses? Do you know that coronaviruses are seasonal viruses? Do you know when they tend to manifest? When the sun is not strong. So guess what, that's autumn and winter, okay? And here's the other interesting thing. It turns out that the innate and cell-mediated immune system do not work well when there are high levels of blood glucose. 

So everybody seems to know that people with COVID tend to be fat and have low vitamin D levels. Now, do you understand why? Here's the flip side of the story. What are the two fastest ways to raise your blood glucose? Most of your listeners will probably say cheesecake or carbohydrates. It turns out, they'd be wrong. The number one way to raise blood glucose faster and the insulin process is unopposed blue light by red light. Those studies have been out in the literature for 34 years, and guess what, none of your endocrinologists, none of your primary care doctors seem to know that. If you go on my Twitter feed, you'll find it posted. I post that slide at least 1000 times a year. And when I point out to people that if you want to get COVID, all you need to do is sit in front of the TV or computer screen, stay inside.

[00:44:22] Ashley James: Oh my gosh that just hit me.

[00:44:25] Dr. Jack Kruse: And here's the big-ticket, remember, vitamin D is a proxy for apoptosis. What is apoptosis? It takes out cells that have been virally infected. Well, guess what, if you don't have a high vitamin D level, do you think your cell-mediated immune system can actually operate? The answer is no. So the longer the virus sits around even though it's not a deadly virus, if the immune functioning in you doesn't work, you fall into what Dr. Fauci wants you to believe, a big pharma solution.

So, who is John Rockefeller today? Dr. Fauci, Birx, Redfield, Pfizer, Moderna, that's who they are, and you need to understand how the game is being played. You're being shown a narrative that on the surface makes sense, but it only makes sense when you understand it from their perspective.

What I like to explain to people is COVID is a compliance test for an economic war that's being waged against patients. So if you have the mindset that COVID is really a deadly virus, you are going to have a victimhood mindset. You are going to be subject to the beliefs of the people that are out there that are going to convince you to roll up your sleeves and get a jab. If on the other hand you understand the linkages back to Rockefeller and how this has been polluted, you'll begin to realize you have a warrior mentality. And the answer for you is to understand how to use or build mitochondrial power or what we call redox power to increase your cell-mediated immune response and your [inaudible 00:45:58] response so that coronavirus is nothing but the flu because that's really what it is.

[00:46:03] Ashley James: And they told us to stay inside. What did everyone do? They didn't get sunlight and they stood in front of their screens for months and months and months.

[00:46:13] Dr. Jack Kruse: And they watched Netflix, and they ate food from Amazon that was not created by photosynthesis. Is it any wonder why we have the outcome we have when you understand the quantum biologic or the mitochondria perspective? Do you understand why I'm pretty popular right now? Because guess what, 15 years ago I was a crazy SOB on the internet. Now, people are beginning to realize, I'm pretty smart. I've dissected this out pretty well. And the thing is right now, what you are being subject to Ashley is something that Plato discovered almost 2500 years ago. It's called the Allegory of the Cave. For the listeners who don't know about it, I'm going to explain it to you.

Viral tyranny is found in that story. Plato tells us a story about a bunch of slaves that are handcuffed to a wall inside a cave where their masters put a fire in there and the fire shows a shadow cast on the wall. They stay in there so long that they come to believe that the environment that they're in is reality. One of the slaves one day breaks his chains, goes outside, and realizes that there's a world outside. It's amazing. What does that slave do? He's faced with a moral dilemma.

Do I go and leave the cave and try to find other people like me who got away, or do I go and try to help the people that are still locked in the cave? The story goes, he goes in and tries to help those people, and what does he find? Those people are perfectly fine to believe what's in the cave. They do not want to go out and help them. What's the moral of the story? Most people whose perception is altered by something, who are not willing to change suffer from something called Stockholm syndrome, and they continue to believe the people who oppress them.

What's the story of the person that left? The person that left has an ethical dilemma. When you understand the ethical dilemma and it has affected you many more times in your life than just this COVID thing, which is exactly how I told you how I figured out the leptin story because that's effectively what happened to me as an allopathic doctor. I began to realize that I needed to question every narrative. And I realized as a lion, I was interested in other lions. I realized that I can't help obedient idiots in the cave who don't want to help themselves. So if you want to roll up your sleeves and think that the big pharma solution to this coronavirus is found at the tip of the needle, good luck. For everybody else who wants to do it nature's way, come follow me.

[00:48:50] Ashley James: Exactly. I mean, the propaganda is so thick. I've studied Trivium and neuro-linguistic programming and understand the linguistic fallacies. So when I read through the media, I can see the propaganda is right there.

[00:49:09] Dr. Jack Kruse: That story too. Most people who are going to hear this podcast don't know where that story began. It began with a guy named Edward Bernays in 1928. And guess what, Mr. Bernays wrote a book in ‘28 called Propaganda. He was a German Jew who wrote this book and immediately, who was the first person that picked it up? It was actually Rockefeller and all his friends that are associated with Hitler in Germany. Joseph Goebbels used everything in Bernay's book to basically get German people to comply. 

This may be a really controversial thing to say on your podcast, you may want to cut it out, I would strongly recommend you don't, but I would tell you the tip of the jab is just like the tip of a tattoo needle that the Jews faced in World War II, why? Ultimately people would say this may be insensitive because we know the outcome for the Jews, we don't know what the outcome for people with the jab is going to be, but the one thing that we do know is that the people that do get the jab are getting way higher rates of problems related to the Messenger RNA vaccines. 

I'm just going to tell you, I don't think it's hyperbole to extrapolate this out further that you have to understand, any level where you’re being affected by propaganda and viral tyranny, you must fight against. And I'm going to tell you, this whole story when you asked me about leptin, I looked at the leptin biology story that I woke up with the same as I look at this COVID score. I was fortunate to be woken up before COVID. Physicians right now still are like those slaves in the cage, and you guys are the public, you have a choice to make. Are you going to continue to be an obedient idiot listening to the people with those shadow casts on the wall, or will you maybe go out and look and see another world that's out there? 

That's the world I'm showing you in this podcast today. It's the world of data. It's a decentralized network that works on light and dark zones. There are so many different ways you break these rules, you just don't realize it. Until you become aware of what you don't know, so that's the Dunning-Kruger Effect, you're much more likely to be programmed, and that's what was the key in Bernay's book. Bernays became a huge sensation because he's the reason why we got Madison Avenue and that advertising, but very few people know that's also how we got fascism in Nazi Germany. 

Most people think it is hyperbole when I say that what's going on in the United States right now mimics exactly to a tee what happened in Germany. And do I believe it will end very much the same way for the American republic if we continue to allow the politicians in Washington D.C. to do what they're doing?

See, the best way for people to fight this is with civil disobedience. And the reason that you're doing that is because science is on your side, meaning nature science, the fundamental laws, the things that we talked about—autophagy, apoptosis—what's the law that belies all of them? A guy named Einstein came up with that and won a Nobel Prize in 1922 called the photoelectric effect. That's the basis of actually what happens photosynthetically. The laws of thermodynamics are axiomatic truths that we found everywhere in the universe. It just doesn't work in Florida, Washington, on Earth, and Jupiter. It works everywhere, contrary to what Dr. Fauci will tell you.

[00:52:46] Ashley James: I'm so glad you're bringing these things up today. This is so, so key for the listeners. Thank you. Thank you so much, and I will not cut out anything you said. I believe in freedom of speech as much as I believe in medical freedom.

[00:53:03] Dr. Jack Kruse: Good.

[00:53:06] Ashley James: So you talked a lot about light, and you also mentioned that water and magnetism essentially are very important. What about 5G? What about the new cell network that's coming around?

[00:53:27] Dr. Jack Kruse: Well, that's light. Remember, 5G is engineered light. So guess what, is engineered light the same as solar light? The answer is no. So, does it have negative correlations? That's right. So that means, the more technology you use and abuse, the worse that your mitochondrial function is going to be.

[00:53:44] Ashley James: Got it. And in terms of water, are you talking about hydrotherapy like using hot and cold water? Are you talking about drinking water?

[00:53:53] Dr. Jack Kruse: Water is a big, big topic. It's the water your mitochondria make that’s the most important. Then the water you drink is much secondary important, why? Because it turns out, the hydrology cycle on the Earth also works on a latitude basis. So, most people know that water is H2O. Most people don't know that there are three isotopes of hydrogen. One is radioactive. That's called tritium. The other one is not radioactive, it's deuterium. And then we have light hydrogen, which is just a hydrogen proton. 

It turns out that deuterium is a proton plus a neutron and I already told you the story that the ATPase uses 3.4 of those light hydrogens to make an ATP. It turns out, when you have deuterium inside the matrix it breaks the ATPase. So you can probably figure out, that's not good for energy or information if you're a mitochondria. And it turns out the way deuterium works when light is poor like it is above the boreal forest, water tends to be deuterium depleted the most. It turns out the worst water in the world is around the equator, and the reason why is because we are able to use more of the light than the water. So, this is even codified in photosynthesis in our foods.

So that's why water and where deuterium is in foods is really important. In fact, I tell doctors—I don't tell patients this—when you look at the enzymatic steps in glycolysis and you’re a physician you go, why in the hell does nature or God put all these nine enzymatic steps in there? The reason is simple. It's trying to avoid deuterium inside the mitochondrial matrix, that's the real reason it does it.

[00:55:31] Ashley James: I got lost. Some water has some form of radioactive hydrogen in it?

[00:55:45] Dr. Jack Kruse: No, no, no. Not radioactive. We don't use radioactive stuff. The story is a story between light, hydrogen, and heavy hydrogen, which is deuterium. It turns out the water on Earth, seawater is 155 parts per million, your mitochondria makes water that is less than 10 parts per million, and the water that's in your blood mimics what's present in the sea. So that means blood and mitochondria have two separate types of water, and it turns out that all of oxidative metabolism—both glycolysis gluconeogenesis—the whole game is to avoid deuterium placement inside the matrix. When you do that, you wind up getting sick. Why? Because you can no longer transfer energy properly or information through the ATP inside the mitochondria.

[00:56:32] Ashley James: So how do you prevent deuterium placement inside the mitochondria?

[00:56:37] Dr. Jack Kruse: It's pretty simple, I already answered that question for you. Live a proper circadian life.

[00:56:41] Ashley James: Got it.

[00:56:43] Dr. Jack Kruse: It turns out that sunlight naturally deuterium depletes water through photosynthesis. That's the reason why circadian biology is the single number one thing for a Black Swan mitochondriac. That's the name of the tribe that I teach.

[00:56:56] Ashley James: Okay. How do listeners join your Black Swan tribe and learn from you?

[00:57:06] Dr. Jack Kruse: Well, to try it out, you can come to my forums. I have a website called jackkruse.com. I have forums there that will overwhelm you. I mean, there's 10 years’ worth of data there where I talk about a variety of different things. But if you want a lot more information in terms of hand-holding and what I do monthly Q&As for my members, that's kruseatdestin.com. I have different groups in there that I use. You can go to that website and see it from there.

[00:57:35] Ashley James: What kind of water do you drink?

[00:57:36] Dr. Jack Kruse: It depends on the season. So right now I'm in the process of the autumnal equinox of changing to more deuterium depleted water. So that means I drink water from higher latitudes when the sun begins to weaken here in Florida.

[00:57:50] Ashley James: So you get your water from different locations?

[00:57:56] Dr. Jack Kruse: Iceland. Icelandic water.

[00:57:59] Ashley James: Got it. You don't put it through any kind of special filter?

[00:58:02] Dr. Jack Kruse: You don't need to. Do the animals do that, so why should you? But I guarantee you, you'll have an allopathic or functional medicine doctor, after listening to this, try to sell you an answer.

[00:58:14] Ashley James: I use a Berkey just because it removes crap, I don't know.

[00:58:22] Dr. Jack Kruse: Yeah. I don't know if I'm such a believer in Berkey. I've done biohacks on them, and to be quite honest with you, I think a lot of the stuff that they tell people is manufactured as a story. If you told me you're doing it, I'm not going to pound you too hard because at least you're trying to do something to help you. And do I think that trying to optimize your water is [inaudible 00:58:49] or as smart as optimizing your diet? Yeah, I do. I believe they're that important. But if you don't get out in the sun, all of those things are a giant waste of money.

[00:59:00] Ashley James: Got it. I love it. Dr. Kruse, thank you so much for coming on the show today and sharing this information. I definitely urge listeners to go to your website, jackkruse.com, and also your Patreon, patreon.com/ DrJackKruse.

[00:59:18] Dr. Jack Kruse: That's where we get the high-level stuff. If you want to learn about the quantum thermodynamics of truly how life works, I have a 28-part series that teaches you all that. That may be a rough drink out of the firehose for people who don't get the basics down. But if you want the basics down, I think you could go read my book. It's 10 years old now. You can buy it on Amazon. It's called the Epi‑Paleo Rx

But I will tell you, the first chapter is an eye-opener. It gets into the reason why I became very pissed off in my profession and really the story behind it is tied to this story of JP Morgan, Andrew Carnegie, and John Rockefeller. So I realized that I've been lied to by my profession for a long time. It doesn't mean it was done with intent. Most of the doctors out there are ignorant of the things that we talked about today. So I don't want any of you to get pissed off at the doctors.

[01:00:11] Ashley James: They don’t know.

[01:00:13] Dr. Jack Kruse: They didn't know and now that I've been talking about this for 16 years, if your doctor hears this and doesn't know, then you should fire him.

[01:00:21] Ashley James: Lastly, my one last question is, if a good friend of yours were to become sick and they think, okay, I've got a coronavirus and they're pretty sick, what advice would you give them?

[01:00:37] Dr. Jack Kruse: Just what I told you today—optimize circadian biology, drink a lot of deuterium depleted water, and avoid a ton of food. You use a lot of fasting because we know that fasting with viruses actually optimizes both autophagy and apoptosis. But again, to do all those things, you really need good sun. Where you are right now in Washington, you don't have that, so the smart answer there is come take a trip down to Mexico or El Salvador. I just got from spending three weeks in El Salvador, and I live at the 28th latitude here in Destin. But I went down to the 13.4 latitude to get a boost towards the end of the summer, and I'm actually planning on potentially opening a clinic down there.

[01:01:25] Ashley James: That sounds wonderful. Well, I look forward to hearing about that clinic that you open up down there. Thank you so much for coming on the show. I love what you share. I learned about what you talked about in terms of the history of the allopathic medical system about 11 years ago and it blew my mind. I've been feeling like I've been living in the Allegory of the Cave just trying to help people wake up to this information. And you're right, those who would rather stay in their servitude will vilify you for trying to bring them the truth.

[01:02:05] Dr. Jack Kruse: Yes, absolutely. And that's one of the things that I faced when I brought this to the Paleo community 15 years ago. I mean, most people don't even know this, but I was one of the keynote speakers, the original Paleo f(x) Conference, and boy they didn't like the message that I brought. And I did the same thing for the first Bulletproof Conference in 2014. Dave Asprey didn't like this message either because if you understand what I'm saying to you, you don't need anything special to be optimal. What you need to do is optimize light, water, and magnetism. And here's the best part of the story, none of that really cost you a lot of money. 

The only thing I really sell people is the information that I shared with you on this podcast. If you want to learn more and you want to get up to speed faster, yeah, it probably would be wiser for you to learn from a guy like me, that's what I'm charging for. I'm charging you for my time, but I'm not going to sell you a pill, a prescription, or something. I'm going to sell you ideas that I learned from nature. And the thing is, if I'm wrong, that means Einstein's wrong, Darwin's wrong, I'm cool with that. But the one thing I can tell you for sure, allopathic medicine, functional medicine, and anybody who sells supplements exclusively, they’re about as useful as the letter G in the word was lasagna.

[01:03:27] Ashley James: Again, I'm so excited for this information to get to my listeners. My listeners are just hungry and thirsty for this knowledge, and I know they'll be excited to continue to learn from you on your forum and on your Patreon. Is there anything that you'd like to say, anything you'd like to share to wrap up today's interview?

[01:03:50] Dr. Jack Kruse: I would tell people one of the things that I've done, if you're a wordsmith and you'd like to read, I would just tell you to probably get my book. Be the Patreon stuff, read the stuff on the forum. But if you're a visual learner and you're not deep in the science, I started a project this year that you might be interested in, it's called Quantum Health TV. In that, I do small little episodes where I talk about aspects of quantum biology and lay it out. I just finished doing a four-hour documentary about mitochondria and deuterium. Since we talked a little bit about it here, if anybody wants to learn more about it, I think if you watched those videos, you’d probably do okay, and I think you can find them at quantumhealth.tv.

[01:04:42] Ashley James: Yeah, quantumhealth.tv is what's in my notes. I'll make sure that all the links are in our show notes.

[01:04:49] Dr. Jack Kruse: I think that one’s good for the visual learners because you know, not everybody likes to read. I tend to be a reader. I'm not really a big fan of video, and you probably know why now because video is not really great for me if I'm looking at a screen. I'd rather read the book out in the sun. But you know, different strokes for different folks. The bottom line is we're trying to get people off of zero. And if you don't know anything about mitochondria and you heard anything in this podcast that intrigued you or interests you, the wise among you will take something you fundamentally don't believe, examine it for yourself, and then decide.

Maybe I can do something else. Maybe this isn't going to be as hard as I thought. Maybe the answer for my autoimmune condition, my cancer, my obesity, or my hyperthyroidism might be found in the message that's buried in light, water, and magnetism. Then I feel like we've done a good job here.

[01:05:47] Ashley James: Excellent. Well, I am really excited to check out your quantumhealth.tv videos because I'm definitely a visual learner, and I am definitely going to go get out in the sunlight after this interview, and I hope everyone else does as well and checks out everything that you do. Thank you, Dr. Kruse. You're welcome back on the show any time you want to share more information. We'd love to have you back.

[01:06:12] Dr. Jack Kruse: No problem. It was fun. Take care.

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Ashley James

Health Coach, Podcast Creator, Homeschooling Mom, Passionate About God & Healing

Ashley James is a Holistic Health Coach, Podcaster, Rapid Anxiety Cessation Expert, and avid Whole Food Plant-Based Home Chef. Since 2005 Ashley has worked with clients to transform their lives as a Master Practitioner and Trainer of Neuro-linguistic Programming.

Her health struggles led her to study under the world’s top holistic doctors, where she reversed her type 2 diabetes, PCOS, infertility, chronic infections, and debilitating adrenal fatigue.

In 2016, Ashley launched her podcast Learn True Health with Ashley James to spread the TRUTH about health and healing. You no longer need to suffer; your body CAN and WILL heal itself when we give it what it needs and stop what is harming it!

The Learn True Health Podcast has been celebrated as one of the top holistic health shows today because of Ashley’s passion for extracting the right information from leading experts and doctors of holistic health and Naturopathic medicine


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